Publications

The Main Publications

• Gonzalez-Fajardo L, Ndaya D, Kasi RM, Lu X. Influence of the method of preparation on the characteristics and performance of cholesterol-based polymeric nanoparticles for redox-triggered release of doxorubicin in tumor cells. International journal of pharmaceutics 2019, 571, 118701

• J.M. Perry, F. Tao, A. Roy, T. Lin, X.C. He, S. Chen, X. Lu, J. Nemechek, L. Ruan, X. Yu, D. Dukes, A. Moran, J. Pace, K. Schroeder, M. Zhao, A. Venkatraman, P. Qian, Z. Li, M. Hembree, A. Paulson, Z. He, D. Xu, T.-H. Tran, P. Deshmukh, C.T. Nguyen, R.M. Kasi, R. Ryan, M. Broward, S. Ding, E. Guest, K. August, A.S. Gamis, A. Godwin, G.S. Sittampalam, S.J. Weir, L. Li, Overcoming Wnt–β-catenin dependent anticancer therapy resistance in leukaemia stem cells, Nat. Cell Biol. 2020,  22: 689–700

• Kashfi-Sadabad R, Gonzalez-Fajardo L, Hargrove D, Ahmadi B, Munteanu D, Shahbazmohamadi S, Jay M and Lu X. Engineering multi-functional gold decorated dendritic mesoporous silica/tantalum oxide nanoparticles for intraperitoneal tumor-specific delivery. Particle and Particle Characterization. 2019, 36(4)  

• Hargrove D, Liang B, Kashfi-Sadabadi R, Joshi GN, Gonzalez-Fajardo L, Glass S, Jay M, Salner A, Lu X, Tumor-Nanoparticle Interactions Following Intraperitoneal Delivery for Targeting Peritoneal Metastasis. Journal of Controlled Release. 2020,  328:846-858

   

• Di Pasqua AJ, Huckle JE, Kim JK, Chung Y, Wang AZ, Jay M and Lu X. Preparation of neutron activatable holmium nanoparticles for the treatment of ovarian cancer metastases. Small. 2012, 8 (7): 997-1000

• Di Pasqua AJ, Miller ML, Lu X, Peng L, Jay M., Tumor accumulation of neutronactivatable holmium-containing mesoporous silica nanoparticles in an orthotopic non-small cell lung cancer mouse model, Inorganica Chimica Acta. 2012, 393: 334–336

• Di Pasqua AJ, Yuan H, Chung Y, Kim JK, Huckle JE, Li C, Sadgrove M, Tran TH, Jay M, Lu X. Neutron-activatable holmium-containing mesoporous silica nanoparticles as a potential radionuclide therapeutic agent for ovarian cancer. Journal of Nuclear Medicine. 2013, 54:111-116

• Fu Q, Hargrove D, Lu X.  Improving Paclitaxel Pharmacokinetics by Using Tumor-Specific Mesoporous Silica nanoparticles with Intraperitoneal Delivery. Nanomedicine: Nanotechnology, Biology, and Medicine. 2016, 12: 1951–1959.

• Kim J, Narayan R, Lu X, Jay M. Neutron-Activatable Needles for Radionuclide Therapy of Solid Tumors. Journal of Biomedical Materials Research Part A. 2017,105(12):3273-3280

• Kim J, Luo ZX, Wu Y, Lu X, Jay M. In-situ formation of holmium oxide in pores of Mesoporous Carbon Nanoparticles as substrates for neutron-activatable radiotherapeutics . Carbon. 2017, 117: 92–99.

• Tran TH, Nguyen CT, Gonzalez-Fajardo L, Hargrove D, Song D, Deshmukh P, Mahajan L, Ndaya D, Lai L, Kasi RM, and Lu X. Long Circulating Self-Assembled Nanoparticles from Cholesterol-Containing Brush-Like Block Copolymers for Improved Drug Delivery to Tumors. Biomacromolecules. 2014, 15 (11): 4363–4375

• Nguyen CT, Tran TH, Lu X, Kasi RM. Self-assembled nanoparticles from thiol functionalized liquid crystalline brush block copolymers for dual encapsulation of doxorubicin and gold nanoparticles. Polymer Chemistry. 2014, 5: 2774-2783

• Nguyen CT, Tran TH, Amiji M, Lu X, Kasi RM. Redox-Sensitive Nanoparticles from Amphiphilic Cholesterol-Based Block Copolymers for Enhanced Tumor Intracellular Release of Doxorubicin. Nanomedicine: Nanotechnology, Biology, and Medicine. 2015, 11(8): 2071–2082

• Gonzalez-Fajardo L, Mahajan LH, Ndaya D, Hargrove D, Manautou JM, Liang BT, Chen MH, Kasi RM, and Lu X . Reduced In Vivo Toxicity of Doxorubicin by Encapsulation in Cholesterol-Containing Self-Assembled Nanoparticles. Pharmacological research. 2016. 107:93-101.